Ecco il contenuto del mio Portfolio.
This is my Portfolio.
The war against SARS-CoV2.
The war against the SARS-CoV2 infection: is it better to fight or mitigate it?
On April 6, we published on Clinical Immunology our theory about the crucial role of Nitric Oxide on the severity of COVID-19: we postulated that in hypertensive, diabetic and obese patients, COVID-19 could be more aggressive/fatal due to a high level of “basal” inflammation with low Nitric Oxide levels. Interestingly, the “protective” effects of several factors (such as estrogens) could play by increasing the formation of endogenous Nitric Oxide.
From a therapeutic point of view, to increase the basal Nitric Oxide levels, we suggested the use of phosphodiesterase type 5 inhibitors, such as intravenous Sildenafil oral Tadalafil, in the treatment of COVID-19. (Clinical Immunology 2020 DOI: 10.1016/j.clim.2020.108414).
Following our suggestions, Ahluwalia and colleagues (Mount Sinai Hospital – New York) SUCCESSFULLY treated an adult congenital heart disease COVID-19 patient with i.v. Sildenafil (JACC: Case Reports 2020 DOI: 10.1016/j.jaccas.2020.05.013).
Let’s start again considering the war against SARS-CoV2 in an alternative way (Dal Moro et al., Medical Hyphoteses 2020): using phosphodiesterase type 5 inhibitors (as prophylaxis?), we don’t fight the virus, but we could mitigate its effects.
published on Clinical Immunology and Medical Hypotheses.
Complete substitution of the left (!) ureter with appendix
We demonstrated that a complete left ureteral substitution with appendix is a feasible and safe technique.
Published on Prog Urol.
How to manage a partial detachment of the ureter during Robotic Radical Prostatectomy?
We present a technique to ensure the successful outcome in cases of a partial detachment of the ureter during Robotic Prostatectomy.
Published on Minerva Urol Nefrol.
The “extreme” bladder neck preservation during Robotic Radical Prostatectomy.
My personal experience
published on Urologia Journal.
R.U.G. – Replacement of the Ureter with Gonadal Vein
My novel technique: R.U.G. – Replacement of the Ureter with Gonadal Vein.
published on Minerva Urol Nefrol.
Fagan’s Nomogram can increase the diagnostic accuracy of predictive tools for Prostate Cancer
“Study of diagnostic accuracy of Fagan’s two-step nomogram
in increasing the value of predictive tools for prostate cancer: application of specific spatial distribution of positive/negative bioptic cores to predict extracapsular extension”
published in Aging Clinical and Experimental Research.
«b-MAP»: A new diagram for reporting data on various areas of an endoscopically evaluated bladder
Starting from an analysis of several videos showing standard examples of diagnostic cystoscopies, I would like to propose a new diagram which graphically describes the bladder (and the prostatic urethra in male patients), called ‘b-MAP’ (bladder-MAP).
It not only allows rapid, precise identification of specific points of interest (essential for standardized reports of cystoscopic findings); it also faithfully reflects all the single steps of a standard cystoscopy.
published in Actas Urologicas Espanola.
A Novel Data Remodeling Model to test the role of mpMRI
“Does 1.5 T mpMRI play a definite role in detection of clinically significant prostate cancer? Findings from a prospective study comparing blind 24-core saturation and targeted biopsies with a novel data remodeling model”
published in Aging Clinical and Experimental Research.
Drawing & Rendering
The Platform for Uro-Residents
P.L.E.A.T. – Preventing Lymphocele Ensuring Absorption Transperitoneally:
A Novel Robotic Technique
Una innovativa tecnica chirurgica robotica per prevenire i linfoceli postoperatori.
A novel robotic technique to prevent the formation of postoperative lymphoceles.
Bladder peritoneum “pleated” along the midline, leaving 2 lateral openings, according to the preventing lymphocele ensuring absorption transperitoneally (P.L.E.A.T.) technique.
First Prize Best Video – ERUS 2017
Atlas of Urologic Surgery – Volume II
Il Secondo Volume del mio Atlante di Chirurgia Urologica.
Volume II of my Atlas of Urologic Surgery.
Robotic Intracorporeal Urinary Diversion
Il risultato di una collaborazione con alcuni tra i maggiori esperti di cistectomia robotica al mondo.
An amazing collaboration!
Published on Minerva Urologica e Nefrologica 2016.
lat. Vesica Patavina
Proposta di una nuova neovescica ileale ortotopica robotica.
A novel robotic intracorporeal ileal orthotopic neobladder.
Published on Urology 2016.
LUCS – Lighting from Urethral (Cystoscope) Side
Nuova tecnica per la visualizzazione della vascolarizzazione intestinale in corso di cistectomia robotica.
A novel technique to visualize intestinal vessels during robotic cystectomy.
Published on International Journal of Urology 2016.
Best Poster @EAU16 – Munich
Cupid and Psyche
Nuova tecnica chirurgica robotica per il trattamento del Prolasso degli Organi Pelvici.
A novel robotic technique to treat Pelvic Organs Prolapse.
ScAPSA – Scoring Adherence to Prostatic Surgical Aims
Proposta di un nuovo sistema per quantificare l’abilità chirurgica in corso di prostatectomia robotica.
A novel scoring system to quantify surgical proficiency during robotic prostatectomy.
A: Non Nerve-Sparing
B: Partial Nerve-Sparing
C: Complete Nerve-Sparing
The Scoring System
L’andamento dei miei primi 25 casi di Prostatectomia Robotica.
My first 25 RARP.
Atlas of Urologic Surgery – Volume I
Il Primo Volume del mio Atlante di Chirurgia Urologica.
Volume I of my Atlas of Urologic Surgery.
CoRPUS – Complete Reconstruction of the Posterior Urethral Support
Una nuova tecnica per migliorare la Continenza Urinaria dopo Prostatectomia Robotica.
A novel original technique to improve urinary continence after robotic prostatectomy.
Published on Urology 2014.
Best Video Prize @EAU2014 – Stockholm.
Best Poster @SIU2014 – Firenze.
Athermal Bladder Neck preservation during Robotic Prostatectomy
La mia “Tecnica gentile” per preservare il collo della vescica durante prostatectomia robotica.
My “Gentle Technique” to preserve bladder neck during robotic prostatectomy.
Published on International Brazilian Journal of Urology 2014.
Un nuovo dispositivo per il controllo dell’emostasi.
A novel hemostatic device.
“HEMOSTATIC DEVICE FOR SURGICAL PROCEDURES AND EMERGENCIES”
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